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DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia

Mutations in DNA methyltransferase 3A (DNMT3A) gene were recently demonstrated in acute myeloid leukemia(AML). Approximately 20% patients with AML carry DNMT3A gene mutations and was associated with a poor clinical outcome. but its clinical implications in Chinese AML patients are largely unknown. W...

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Detalhes bibliográficos
Main Authors: Lu, Quanyi, Chen, Yamei, Wang, Hang, Li, Zhipeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605177/
https://ncbi.nlm.nih.gov/pubmed/23305405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-1
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