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A mutation outside the two zinc fingers of ADR1 can suppress defects in either finger.

A second-site mutation that restored DNA binding to ADR1 mutants altered at different positions in the two zinc fingers was identified. This mutation (called IS1) was a conservative change of arginine 91 to lysine in a region amino terminal to the two zinc fingers and known from previous experiments...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Camier, S, Kacherovsky, N, Young, E T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1448103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5758-5767.1992
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