A mutation outside the two zinc fingers of ADR1 can suppress defects in either finger.
A second-site mutation that restored DNA binding to ADR1 mutants altered at different positions in the two zinc fingers was identified. This mutation (called IS1) was a conservative change of arginine 91 to lysine in a region amino terminal to the two zinc fingers and known from previous experiments...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1448103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5758-5767.1992 |
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