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Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage

The relationship of HIV tropism with disease progression and the recent development of CCR5-blocking drugs underscore the importance of monitoring virus coreceptor usage. As an alternative to costly phenotypic assays, computational methods aim at predicting virus tropism based on the sequence and st...

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Bibliografiska uppgifter
Huvudupphovsmän: Bozek, Katarzyna, Lengauer, Thomas, Sierra, Saleta, Kaiser, Rolf, Domingues, Francisco S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605109/
https://ncbi.nlm.nih.gov/pubmed/23555214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002977
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