GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures

BACKGROUND: Geneticists who look beyond single locus disease associations require additional strategies for the detection of complex multi-locus effects. Epistasis, a multi-locus masking effect, presents a particular challenge, and has been the target of bioinformatic development. Thorough evaluatio...

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Hauptverfasser: Urbanowicz, Ryan J, Kiralis, Jeff, Sinnott-Armstrong, Nicholas A, Heberling, Tamra, Fisher, Jonathan M, Moore, Jason H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Methodology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605108/
https://ncbi.nlm.nih.gov/pubmed/23025260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-5-16
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