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Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development
Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney development using a conditional knockout strategy that specifically inactivated Yap within the nephrogenic lineage. We found...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605093/ https://ncbi.nlm.nih.gov/pubmed/23555292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003380 |
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