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The Effects of Epidermal Growth Factor Receptor and Insulin-like Growth Factor 1 Receptor Inhibition On Proliferation and Intracellular Signaling In cSCCHN: Potential for Dual Inhibition As a Therapeutic Modality
BACKGROUND: Combined inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor 1 (IGF1R) has been proposed as a therapy for cutaneous squamous cell carcinoma of the head and neck (cSCCHN). METHODS: Receptor expression and downstream signaling was assessed in cSCC...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605039/ https://ncbi.nlm.nih.gov/pubmed/22495823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.22936 |
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