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The Effects of Epidermal Growth Factor Receptor and Insulin-like Growth Factor 1 Receptor Inhibition On Proliferation and Intracellular Signaling In cSCCHN: Potential for Dual Inhibition As a Therapeutic Modality

BACKGROUND: Combined inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor 1 (IGF1R) has been proposed as a therapy for cutaneous squamous cell carcinoma of the head and neck (cSCCHN). METHODS: Receptor expression and downstream signaling was assessed in cSCC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Clayburgh, Daniel R, Gross, Neil D, Proby, Charlotte, Koide, Jade, Wong, Melissa H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605039/
https://ncbi.nlm.nih.gov/pubmed/22495823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.22936
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