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Endothelial Cell Whole Genome Expression Analysis in a Mouse Model of Early-Onset Fuchs' Endothelial Corneal Dystrophy

PURPOSE. To investigate the endothelial gene expression profile in a Col8a2 Q455K mutant knock-in mouse model of early-onset Fuchs' endothelial corneal dystrophy (FECD) and identify potential targets that can be correlated to human late-onset FECD. METHODS. Diseased or normal endothelial phenot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matthaei, Mario, Hu, Jianfei, Meng, Huan, Lackner, Eva-Maria, Eberhart, Charles G., Qian, Jiang, Hao, Haiping, Jun, Albert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604908/
https://ncbi.nlm.nih.gov/pubmed/23449721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10898
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