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Using False Discovery Rates to Benchmark SNP-callers in next-generation sequencing projects

Sequence alignments form the basis for many comparative and population genomic studies. Alignment tools provide a range of accuracies dependent on the divergence between the sequences and the alignment methods. Despite widespread use, there is no standard method for assessing the accuracy of a datas...

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Detalhes bibliográficos
Main Authors: Farrer, Rhys A., Henk, Daniel A., MacLean, Dan, Studholme, David J., Fisher, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604800/
https://ncbi.nlm.nih.gov/pubmed/23518929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01512
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