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Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain
Small RNAs regulate genetic networks through a ribonucleo-protein complex called the RNA-induced silencing complex (RISC), which, in mammals, contains at its center one of four Argonaute proteins (Ago1–Ago4) (reviewed in [1–4]). A key regulatory event in the RNA interference (RNAi) and microRNA (miR...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604743/ https://ncbi.nlm.nih.gov/pubmed/22795694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.06.040 |
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