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End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1

In eukaryotes, permanent inhibition of the non-homologous end joining (NHEJ) repair pathway at telomeres ensures that chromosome ends do not fuse. In budding yeast, binding of Rap1 to telomere repeats establishes NHEJ inhibition. Here, we show that the Uls1 protein is required for the maintenance of...

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Detalhes bibliográficos
Main Authors: Lescasse, Rachel, Pobiega, Sabrina, Callebaut, Isabelle, Marcand, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604719/
https://ncbi.nlm.nih.gov/pubmed/23417015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.24
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