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End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1
In eukaryotes, permanent inhibition of the non-homologous end joining (NHEJ) repair pathway at telomeres ensures that chromosome ends do not fuse. In budding yeast, binding of Rap1 to telomere repeats establishes NHEJ inhibition. Here, we show that the Uls1 protein is required for the maintenance of...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604719/ https://ncbi.nlm.nih.gov/pubmed/23417015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.24 |
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