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Signal recognition initiates reorganization of the presequence translocase during protein import

The mitochondrial presequence translocase interacts with presequence-containing precursors at the intermembrane space (IMS) side of the inner membrane to mediate their translocation into the matrix. Little is known as too how these matrix-targeting signals activate the translocase in order to initia...

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Main Authors: Lytovchenko, Oleksandr, Melin, Jonathan, Schulz, Christian, Kilisch, Markus, Hutu, Dana P, Rehling, Peter
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604718/
https://ncbi.nlm.nih.gov/pubmed/23403928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.23
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