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Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction.

We have used a dominant inhibitory ras mutant (Ha-ras Asn-17) to investigate the relationship of Ras proteins to hydrolysis of phosphatidylcholine (PC) in the transduction of mitogenic signals. Expression of Ha-Ras Asn-17 inhibited NIH 3T3 cell proliferation induced by polypeptide growth factors or...

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Published in:Mol Cell Biol
Main Authors: Cai, H, Erhardt, P, Szeberényi, J, Diaz-Meco, M T, Johansen, T, Moscat, J, Cooper, G M
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1992
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1448068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5329-5335.1992
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