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SILAC-based proteomic analysis to investigate the impact of amyloid precursor protein expression in neuronal-like B103 cells

Alzheimer’s disease (AD) is the most prevalent form of dementia in the elderly. Amyloid plaque formation through aggregation of the amyloid beta peptide derived from amyloid precursor protein (APP) is considered one of the hallmark processes leading to AD pathology; however, the precise role of APP...

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Detalhes bibliográficos
Main Authors: Chaput, Dale, Kirouac, Lisa Hornbeck, Bell-Temin, Harris, Stevens, Stanley M., Padmanabhan, Jaya
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604657/
https://ncbi.nlm.nih.gov/pubmed/23161580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201200251
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