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Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints.

Using a combination of in vivo footprinting and site-directed mutagenesis, we have functionally characterized an enhancer located 12 kb downstream of the human immunoglobulin kappa constant-region gene. The core enhancer region is highly homologous to the murine 3' kappa enhancer. However, in a...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Judde, J G, Max, E E
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360454/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5206
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