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Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints.

Using a combination of in vivo footprinting and site-directed mutagenesis, we have functionally characterized an enhancer located 12 kb downstream of the human immunoglobulin kappa constant-region gene. The core enhancer region is highly homologous to the murine 3' kappa enhancer. However, in additi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Judde, J G, Max, E E
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360454/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5206-5216.1992
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