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TFIIA induces conformational changes in TFIID via interactions with the basic repeat.

DNA-binding studies with Saccharomyces cerevisiae TFIID point mutants indicated that TFIIA interacts with the basic repeat region of TFIID and induces structural changes. The latter was shown by the ability of TFIIA to compensate for TFIID point mutants defective for DNA binding. Interaction with TF...

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Publicat a:Mol Cell Biol
Autors principals: Lee, D K, DeJong, J, Hashimoto, S, Horikoshi, M, Roeder, R G
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360452/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5189-5196.1992
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