TFIIA induces conformational changes in TFIID via interactions with the basic repeat.

DNA-binding studies with Saccharomyces cerevisiae TFIID point mutants indicated that TFIIA interacts with the basic repeat region of TFIID and induces structural changes. The latter was shown by the ability of TFIIA to compensate for TFIID point mutants defective for DNA binding. Interaction with TF...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Lee, D K, DeJong, J, Hashimoto, S, Horikoshi, M, Roeder, R G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC360452/
https://ncbi.nlm.nih.gov/pubmed/1406690
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