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Functional asymmetry of the regions juxtaposed to the membrane-binding sequence of polyomavirus middle T antigen.

The functional importance of the two clusters of positively charged amino acids which flank the hydrophobic membrane-anchoring sequence of polyomavirus middle T (mT) protein has been investigated by using site-directed mutagenesis. A clear asymmetry was apparent. No effect on transformation was seen...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Dahl, J, Thathamangalam, U, Freund, R, Benjamin, T L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406680/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5050
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