Transcriptome Sequencing of Tumor Subpopulations Reveals a Spectrum of Therapeutic Options for Squamous Cell Lung Cancer

BACKGROUND: The only therapeutic options that exist for squamous cell lung carcinoma (SCC) are standard radiation and cytotoxic chemotherapy. Cancer stem cells (CSCs) are hypothesized to account for therapeutic resistance, suggesting that CSCs must be specifically targeted. Here, we analyze the tran...

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Main Authors: Barrett, Christian L., Schwab, Richard B., Jung, HyunChul, Crain, Brian, Goff, Daniel J., Jamieson, Catriona H. M., Thistlethwaite, Patricia A., Harismendy, Olivier, Carson, Dennis A., Frazer, Kelly A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604164/
https://ncbi.nlm.nih.gov/pubmed/23527012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058714
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