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Inhibition of Farnesoid X Receptor Controls Esophageal Cancer Cell Growth In Vitro and in Nude Mouse Xenografts
BACKGROUND: Gastroesophageal reflux is a risk factor for esophageal adenocarcinoma and bile acid and its farnesoid X receptor (FXR) have been implicated in esophageal tumorigenesis. We investigated the role of FXR expression and activity in esophageal cancer initiation and growth. METHODS: FXR expre...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604152/ https://ncbi.nlm.nih.gov/pubmed/23280144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27910 |
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