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Inhibition of Farnesoid X Receptor Controls Esophageal Cancer Cell Growth In Vitro and in Nude Mouse Xenografts

BACKGROUND: Gastroesophageal reflux is a risk factor for esophageal adenocarcinoma and bile acid and its farnesoid X receptor (FXR) have been implicated in esophageal tumorigenesis. We investigated the role of FXR expression and activity in esophageal cancer initiation and growth. METHODS: FXR expre...

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Bibliografiset tiedot
Päätekijät: Guan, Baoxiang, Li, Hao, Yang, Zhengduo, Hoque, Ashraful, Xu, Xiaochun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604152/
https://ncbi.nlm.nih.gov/pubmed/23280144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27910
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