Soluble Guanylate Cyclase α(1)–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α(1) subunit of the nitric oxide receptor soluble guanylate cyclase represent a novel and translatable ani...

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Hlavní autoři: Buys, Emmanuel S., Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R., Jones, Alexander, Tainsh, Laurel T., Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E. T., Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J., Kang, Jae H., Lin, Charles P., Gong, Haiyan, Rhee, Douglas J., Brouckaert, Peter, Wiggs, Janey L., Gregory, Meredith S., Pasquale, Louis R., Bloch, Kenneth D., Ksander, Bruce R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603933/
https://ncbi.nlm.nih.gov/pubmed/23527308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060156
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