Soluble Guanylate Cyclase α(1)–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α(1) subunit of the nitric oxide receptor soluble guanylate cyclase represent a novel and translatable ani...

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主要な著者: Buys, Emmanuel S., Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R., Jones, Alexander, Tainsh, Laurel T., Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E. T., Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J., Kang, Jae H., Lin, Charles P., Gong, Haiyan, Rhee, Douglas J., Brouckaert, Peter, Wiggs, Janey L., Gregory, Meredith S., Pasquale, Louis R., Bloch, Kenneth D., Ksander, Bruce R.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603933/
https://ncbi.nlm.nih.gov/pubmed/23527308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060156
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