Soluble Guanylate Cyclase α(1)–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α(1) subunit of the nitric oxide receptor soluble guanylate cyclase represent a novel and translatable ani...

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Main Authors: Buys, Emmanuel S., Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R., Jones, Alexander, Tainsh, Laurel T., Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E. T., Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J., Kang, Jae H., Lin, Charles P., Gong, Haiyan, Rhee, Douglas J., Brouckaert, Peter, Wiggs, Janey L., Gregory, Meredith S., Pasquale, Louis R., Bloch, Kenneth D., Ksander, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603933/
https://ncbi.nlm.nih.gov/pubmed/23527308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060156
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