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Activating Somatic FGFR2 Mutations in Breast Cancer
It is known that FGFR2 gene variations confer a risk for breast cancer. FGFR2 and FGF10, the main ligand of FGFR2, are both overexpressed in 5–10% of breast tumors. In our study, we sequenced the most important coding regions of FGFR2 in somatic tumor tissue of 140 sporadic breast cancer patients an...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3603931/ https://ncbi.nlm.nih.gov/pubmed/23527311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060264 |
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