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Sequences in the human c-myc P2 promoter affect the elongation and premature termination of transcripts initiated from the upstream P1 promoter.

A conditional block to transcription elongation provides one mechanism for controlling the steady-state levels of c-myc RNA in mammalian cells. Although prematurely terminated c-myc RNAs are not detectable in mammalian cells, truncated c-myc RNAs with 3' ends that map near the end of the first...

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Detalles Bibliográficos
Main Authors: Meulia, T, Krumm, A, Spencer, C, Groudine, M
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC360386/
https://ncbi.nlm.nih.gov/pubmed/1406649
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