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Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells.

beta-cell type-specific expression of the upstream glucokinase promoter was studied by transfection of fusion genes and analysis of DNA-protein interactions. A construct containing 1,000 bp of 5'-flanking DNA was efficiently expressed in HIT M2.2.2 cells, a beta-cell-derived line that makes bot...

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Sonraí Bibleagrafaíochta
Main Authors: Shelton, K D, Franklin, A J, Khoor, A, Beechem, J, Magnuson, M A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC360385/
https://ncbi.nlm.nih.gov/pubmed/1406648
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