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Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells.
beta-cell type-specific expression of the upstream glucokinase promoter was studied by transfection of fusion genes and analysis of DNA-protein interactions. A construct containing 1,000 bp of 5'-flanking DNA was efficiently expressed in HIT M2.2.2 cells, a beta-cell-derived line that makes bot...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1992
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4578 |
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