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The MRF4 activation domain is required to induce muscle-specific gene expression.

MRF4 is a member of the basic helix-loop-helix muscle regulatory factor family that also includes MyoD, myogenin, and Myf-5. Overexpression of MRF4 or the other muscle regulatory factors in fibroblasts converts the cells to differentiated muscle fibers and transcriptionally activates expression of e...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Mak, K L, To, R Q, Kong, Y, Konieczny, S F
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4334-4346.1992
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