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The MRF4 activation domain is required to induce muscle-specific gene expression.

MRF4 is a member of the basic helix-loop-helix muscle regulatory factor family that also includes MyoD, myogenin, and Myf-5. Overexpression of MRF4 or the other muscle regulatory factors in fibroblasts converts the cells to differentiated muscle fibers and transcriptionally activates expression of e...

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Detalles Bibliográficos
Main Authors: Mak, K L, To, R Q, Kong, Y, Konieczny, S F
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC360357/
https://ncbi.nlm.nih.gov/pubmed/1328851
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