Reducing bias in bacterial community analysis of lower respiratory infections

High-throughput pyrosequencing and quantitative PCR (Q-PCR) analysis offer greatly improved accuracy and depth of characterisation of lower respiratory infections. However, such approaches suffer from an inability to distinguish between DNA derived from viable and non-viable bacteria. This discrimin...

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Bibliografische gegevens
Hoofdauteurs: Rogers, Geraint B, Cuthbertson, Leah, Hoffman, Lucas R, Wing, Peter AC, Pope, Christopher, Hooftman, Danny A P, Lilley, Andrew K, Oliver, Anna, Carroll, Mary P, Bruce, Kenneth D, van der Gast, Christopher J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603400/
https://ncbi.nlm.nih.gov/pubmed/23190732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2012.145
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