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Protein Structure Refinement through Structure Selection and Averaging from Molecular Dynamics Ensembles

A molecular dynamics (MD) simulation based protocol for structure refinement of template-based model predictions is described. The protocol involves the application of restraints, ensemble averaging of selected subsets, interpolation between initial and refined structures, and assessment of refineme...

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Hlavní autoři: Mirjalili, Vahid, Feig, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603382/
https://ncbi.nlm.nih.gov/pubmed/23526422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct300962x
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