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Physics Based Protein Structure Refinement through Multiple Molecular Dynamics Trajectories and Structure Averaging

We used molecular dynamics (MD) simulations for structure refinement of CASP10 targets. Refinement was achieved by selecting structures from the MD-based ensembles followed by structural averaging. The overall performance of this method in CASP10 is described and specific aspects are analyzed in det...

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Détails bibliographiques
Auteurs principaux: Mirjalili, Vahid, Noyes, Keenan, Feig, Michael
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212311/
https://ncbi.nlm.nih.gov/pubmed/23737254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24336
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