Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae.

Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) by phosphatidylinositol-specific phospholipase C (PI-PLC) generates two second messengers, inositol 1,4,5-trisphosphate and 1,2-diacylglycerol. The polymerase chain reaction was used to isolate a Saccharomyces cerevisiae gene (PLC1) that enc...

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Publicat a:Mol Cell Biol
Autors principals: Flick, J S, Thorner, J
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5861
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