The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction.

We examined in detail the DNA interaction of the nuclear receptors NGFI-B and steroidogenic factor 1 (SF-1) by using a series of gain-of-function domain swaps. NGFI-B bound with high affinity as a monomer to a nearly linear DNA molecule. The prototypic zinc modules interacted with a half-site of the...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Wilson, T E, Fahrner, T J, Milbrandt, J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5794-5804.1993
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