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The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction.

We examined in detail the DNA interaction of the nuclear receptors NGFI-B and steroidogenic factor 1 (SF-1) by using a series of gain-of-function domain swaps. NGFI-B bound with high affinity as a monomer to a nearly linear DNA molecule. The prototypic zinc modules interacted with a half-site of the...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Wilson, T E, Fahrner, T J, Milbrandt, J
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360322/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395013/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5794
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