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Prorenin Receptor in Distal Nephron Segments of 2-Kidney, 1-Clip Goldblatt Hypertensive Rats

BACKGROUND: The prorenin receptor (PRR) is expressed in the kidneys and has been localized to mesangial cells, renal arterioles, and distal nephron segments. By binding renin or prorenin, this receptor increases renin catalytic activity and activates prorenin. The renin gene is expressed by the prin...

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Autores principales: Prieto, Minolfa C., Botros, Fady T., Kavanagh, Kimberly, Navar, L. Gabriel
Formato: Artigo
Lenguaje:Inglês
Publicado: the Academic Division of Ochsner Clinic Foundation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603183/
https://ncbi.nlm.nih.gov/pubmed/23532382
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