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Stimulators of Soluble Guanylyl Cyclase: Future Clinical Indications

BACKGROUND: Soluble guanylyl cyclase (sGC) is expressed in mammalian cytoplasm and catalyzes the synthesis of the second messenger guanosine 3′,5′-monophosphate (cGMP) involved in important physiological functions such as relaxation of vascular smooth muscle, inhibition of platelet aggregation, modu...

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Autori principali: Nossaman, Bobby D., Kadowitz, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: the Academic Division of Ochsner Clinic Foundation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603178/
https://ncbi.nlm.nih.gov/pubmed/23532174
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