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In Vitro and In Vivo Metabolic Studies of Phospho-aspirin (MDC-22)
PURPOSE: To investigate the metabolism of phospho-aspirin (PA, MDC-22), a novel anti-cancer and anti-inflammatory agent. METHODS: The metabolism of PA was studied in the liver and intestinal microsomes from mouse, rat and human. RESULTS: PA is rapidly deacetylated to phospho-salicylic acid (PSA), wh...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602912/ https://ncbi.nlm.nih.gov/pubmed/22782648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0821-6 |
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