Resistome analysis of Mycobacterium tuberculosis: Identification of aminoglycoside 2'-Nacetyltransferase (AAC) as co-target for drug desigining

The emergence of multidrug resistant tuberculosis (MDRTB) highlights the urgent need to understand the mechanisms of resistance to the drugs and to develop a new arena of therapeutics to treat the disease. Ethambutol, isonazid, pyrazinamide, rifampicin are first line of drugs against TB, whereas ami...

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Autores principales: Joshi, Rakesh S, Jamdhade, Mahendra D, Sonawane, Mahesh S, Giri, Ashok P
Formato: Artigo
Lenguaje:Inglês
Publicado: Biomedical Informatics 2013
Materias:
Hypothesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602886/
https://ncbi.nlm.nih.gov/pubmed/23519100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009174
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