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Conformational Contribution to Thermodynamics of Binding in Protein-Peptide Complexes through Microscopic Simulation

We extract the thermodynamics of conformational changes in biomacromolecular complexes from the distributions of the dihedral angles of the macromolecules. These distributions are obtained from the equilibrium configurations generated via all-atom molecular dynamics simulations. The conformational t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Das, Amit, Chakrabarti, J., Ghosh, Mahua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602779/
https://ncbi.nlm.nih.gov/pubmed/23528087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.058
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