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Tilting and Wobble of Myosin V by High-Speed Single-Molecule Polarized Fluorescence Microscopy

Myosin V is biomolecular motor with two actin-binding domains (heads) that take multiple steps along actin by a hand-over-hand mechanism. We used high-speed polarized total internal reflection fluorescence (polTIRF) microscopy to study the structural dynamics of single myosin V molecules that had be...

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Detalhes bibliográficos
Main Authors: Beausang, John F., Shroder, Deborah Y., Nelson, Philip C., Goldman, Yale E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602762/
https://ncbi.nlm.nih.gov/pubmed/23528086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.057
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