Sustained adenosine exposure causes lung endothelial apoptosis: a possible contributor to cigarette smoke-induced endothelial apoptosis and lung injury

Pulmonary endothelial cell (EC) apoptosis has been implicated in the pathogenesis of emphysema. Cigarette smoke (CS) causes lung EC apoptosis and emphysema. In this study, we show that CS exposure increased lung tissue adenosine levels in mice, an effect associated with increased lung EC apoptosis a...

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Главные авторы: Lu, Qing, Sakhatskyy, Pavlo, Newton, Julie, Shamirian, Paul, Hsiao, Vivian, Curren, Sean, Gabino Miranda, Gustavo Andres, Pedroza, Mesias, Blackburn, Michael R., Rounds, Sharon
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602741/
https://ncbi.nlm.nih.gov/pubmed/23316066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00161.2012
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