Cigarette smoke-induced lung endothelial apoptosis and emphysema is associated with impairment of FAK and eIF2α

Lung endothelial cell (EC) apoptosis has been implicated in the pathogenesis of emphysema. However, the mechanism underlying cigarette smoke (CS)-induced lung EC apoptosis and emphysema is not well defined. We have previously shown that cigarette smoke extract (CSE) decreased focal adhesion kinase (...

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Huvudupphovsmän: Sakhatskyy, Pavlo, Gabino Miranda, Gustavo Andres, Newton, Julie, Lee, Chun Geun, Choudhary, Gaurav, Vang, Alexander, Rounds, Sharon, Lu, Qing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185927/
https://ncbi.nlm.nih.gov/pubmed/24853558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2014.05.003
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