Altered V-ATPase expression in renal intercalated cells isolated from B1 subunit-deficient mice by fluorescence-activated cell sorting

Unlike human patients with mutations in the 56-kDa B1 subunit isoform of the vacuolar proton-pumping ATPase (V-ATPase), B1-deficient mice (Atp6v1b1(−/−)) do not develop metabolic acidosis under baseline conditions. This is due to the insertion of V-ATPases containing the alternative B2 subunit isofo...

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Detalhes bibliográficos
Main Authors: Vedovelli, Luca, Rothermel, John T., Finberg, Karin E., Wagner, Carsten A., Azroyan, Anie, Hill, Eric, Breton, Sylvie, Brown, Dennis, Păunescu, Teodor G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602708/
https://ncbi.nlm.nih.gov/pubmed/23269648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00394.2012
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