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Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis

Clear cells express the vacuolar proton-pumping H(+)-ATPase (V-ATPase) and acidify the lumen of the epididymis, a process that is essential for male fertility. The renin-angiotensin-aldosterone system (RAAS) regulates fluid and electrolyte balance in the epididymis, and a previous study showed bindi...

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Autors principals: Roy, Jeremy W., Hill, Eric, Ruan, Ye Chun, Vedovelli, Luca, Păunescu, Teodor G., Brown, Dennis, Breton, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891217/
https://ncbi.nlm.nih.gov/pubmed/23761626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00410.2012
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