Overexpression of Mos, Ras, Src, and Fos inhibits mouse mammary epithelial cell differentiation.

Mammary epithelial cells terminally differentiate in response to lactogenic hormones. We present evidence that oncoprotein overexpression is incompatible with this hormone-inducible differentiation and results in striking cellular morphological changes. In mammary epithelial cells in culture, lactog...

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Autores principales: Jehn, B, Costello, E, Marti, A, Keon, N, Deane, R, Li, F, Friis, R R, Burri, P H, Martin, F, Jaggi, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC360266/
https://ncbi.nlm.nih.gov/pubmed/1508191
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