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Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse

There are large inter- and intraspecies differences in susceptibility to dioxin-induced toxicities. A critical question in risk assessment of dioxin and related compounds is whether humans are sensitive or resistant to their toxicities. The diverse responses of mammals to dioxin are strongly influen...

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Detalhes bibliográficos
Main Authors: Moriguchi, Takashi, Motohashi, Hozumi, Hosoya, Tomonori, Nakajima, Osamu, Takahashi, Satoru, Ohsako, Seiichiroh, Aoki, Yasunobu, Nishimura, Noriko, Tohyama, Chiharu, Fujii-Kuriyama, Yoshiaki, Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156256/
https://ncbi.nlm.nih.gov/pubmed/12730383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1037886100
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