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Genetic transfer and expression of reconstructed yeast artificial chromosomes containing normal and translocated BCL2 proto-oncogenes.

The goal of this study was to determine whether it will be feasible to study the expression of a large, human gene, such as the BCL2 proto-oncogene, by DNA transfection. The BCL2 proto-oncogene is 230 kb in size and is deregulated in tumor cells by translocation into the immunoglobulin heavy-chain l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Silverman, G A, Yang, E, Proffitt, J H, Zutter, M, Korsmeyer, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8355694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5469
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