Identification of Small Molecule Activators of BMP Signaling

Bone Morphogenetic Proteins (BMPs) are morphogens that play a major role in regulating development and homeostasis. Although BMPs are used for the treatment of bone and kidney disorders, their clinical use is limited due to the supra-physiological doses required for therapeutic efficacy causing seve...

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Autores principales: Vrijens, Karen, Lin, Wenwei, Cui, Jimmy, Farmer, Dana, Low, Jonathan, Pronier, Elodie, Zeng, Fu-Yue, Shelat, Anang A., Guy, Kiplin, Taylor, Michael R., Chen, Taosheng, Roussel, Martine F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602516/
https://ncbi.nlm.nih.gov/pubmed/23527084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059045
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